The core technology of FlowSIGMA was developed and implemented in order to assure efficient and reliable execution of image-based analytics. The system was built to enable an algorithm for identifying changes in brain tumor patients using MRI examinations. This is much more complex than simple routing or forwarding, as it requires recognition that several specific series be present to constitute the specific examination, and it requires querying the archive to determine that a prior examination of this special type is available. It also 'time boxes' the analytic, meaning that if the analytic takes more than a pre-specified amount of time, an error-handling workflow (e.g. notify Support Services) can be executed.